In vivo hair growth-promoting effect of rice bran extract prepared by supercritical carbon dioxide fluid.

Genotoxicity of rice bran oil extracted by supercritical CO2 extraction.

Rice bran oil extracted by supercritical CO2 extraction (RB-SCE) reportedly exhibits pharmacological activities such as antioxidant and in vivo hair growth-inducing effects. Such activities raise the possibility of the development of novel hair growth-inducing agents using RB-SCE. The aim of this study was to investigate the potential genotoxic effects of RB-SCE in three short-term mutagenicity...

Novel fractionation method for squalene and phytosterols contained in the deodorization distillate of rice bran oil.

Since deodorization distillate, a by-product of rice bran oil production, contains squalene (ca. 8%) and phytosterols (ca. 4%) as unsaponifiable components, the concentration of those materials for their use in the cosmetics and food industries is desirable. In the present work, a novel fractionation method of concentrating squalene and phytosterols from deodorization distillate or the unsaponi...

Supercritical Fluid Extraction of Lovastatin from the Wheat Bran Obtained after Solid-State Fermentation

The objective of the present work is to extract lovastatin with minimum impurity by using supercritical carbon dioxide (SC-CO2). A strain of Aspergillus terreus UV 1617 was used to produce lovastatin by solid-state fermentation (SSF) on wheat bran as a solid substrate. Extraction of lovastatin and its hydroxy acid form was initially carried out using organic solvents. Among the different screen...

Rice Bran Oil Extraction with Supercritical Fluid (sfe) to Obtain Enriched Tocopherols and Tocotrienols Fractions

Parboiled rice bran oil was obtained using supercritical CO2 under different conditions of temperature (2°C to 40°C) and pressure (25 to 200 bar). In this study the experiments were carried out with two separators coupled to the extractor. The temperature levels in the first separator were 25°C and 40°C and in the second it was maintained constant at 2°C. The pressures in the first separator we...

Vetiver Oil Extraction Optimization Using Supercritical Carbon Dioxide Fluid